Product name: Forsythiaside

Synonym name: Forsythoside A
Catalogue No.: BP0594
Cas No.: 79916-77-1
Formula: C₂₉H₃₆O₁₅
Mol Weight: 624.592
Botanical Source: Forsythia suspensa （Thunb.） Vahl
Physical Description:
Type of Compound: Phenylpropanoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle

Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.

The product could be supplied from milligrams to grams
Inquire for bulk scale.

Description:

Forsythoside A possesses strong antibacterial, antiinflammatory, antioxidant and antiviral effects. it has the potential to prevent IBV infection in vitro, it can promote the expression of IFN-α and Mx1 significantly.Forsythoside A has inductive effects on the activities of CYP1A2 and CYP2C11, without affecting CYP2D1 and CYP3A1/2 activities.

References:

Phytother Res. 2011 Mar;25(3):338-42.    

Forsythoside a inhibits the avian infectious bronchitis virus in cell culture.    

Forsythoside A is a polyphenolic constituent of the fruits of Forsythia suspensa Vahl. which is widely used as an antiinflammatory agent in traditional Chinese medicine. 

METHODS AND RESULTS:

In the present study, the effects of Forsythoside A on cell infection by avian infectious bronchitis virus were assessed. A real-time fluorescence quantitative PCR assay was used to determine mRNA content of IBV N gene. The pretreatment of cells with Forsythoside A, adding Forsythoside A post infection of cells, and treatment of virus with Forsythoside A were analysed. The inhibitory effect of Forsythoside A was confirmed by infecting primary chicken embryo kidney cells. Infected cells were inhibited by Forsythoside A treatment. 

CONCLUSIONS:

The data indicated that Forsythoside A has the potential to prevent IBV infection in vitro.    

HPLC of  Forsythoside A