Product name: cis-Khellactone Synonym name: Catalogue No.: BP2196 Cas No.: 15645-11-1 Formula: C14H14O5 Mol Weight: 262.261 Botanical Source: Type of Compound:
Purity: 95%~99% Analysis Method: HPLC-DAD or/and HPLC-ELSD Identification Method: Mass, NMR Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage. Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams Inquire for bulk scale.
Khellactone is a coumarin derivative that has been shown to have cytotoxic properties and inhibit the proliferation of cancer cells in vitro. Khellactone has also been shown to stimulate bone formation by regulating bone matrix proteins, which may be due to its ability to up-regulate signal pathways such as NF-κB, WNT, and MAPKs. The potent induction of chronic cough by khellactone may be due to its inhibition of mitochondrial membrane potential. This compound also inhibits the activity of protein kinase C, which regulates signal pathways such as PKC-δ, PKC-ε, and PKC-βII.
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