Product name: Ergothionine Synonym name: L-(+)-Ergothioneine; Ergothioneine；Phytothioneine；Sympectothion Catalogue No.: BP4513 Cas No.: 497-30-3 Formula: C9H15N3O2S Mol Weight: 229.298 Botanical Source: Type of Compound:
Purity: 99% Analysis Method: HPLC-DAD or/and HPLC-ELSD Identification Method: Mass, NMR Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams, up to kilograms. Inquire for bulk scale.
L-Ergothioneine is a stable antioxidant that can be found under conditions of excessive oxidative stress in plant and animal tissue. L-ergothioneine has the ability to scavenge free radicals and protect cells from UV-induced ROS with higher efficiency than antioxidants coenzyme Q(10) or idebenone, thus making it more effective antioxidant. The compound has been shown to be a non-toxic thiol buffering antioxidant, enhance cell viability induced by hydrogen peroxide (H2O2), and inhibit DNA oxidation by peroxynitrite (ONOO-) in the human neuronal hybridoma cell line (N-18-RE-105). L-(+)-Ergothioneine is a naturally-occurring amino acid derived from histidine via hercynine.1 Ergothioneine is a stable antioxidant that scavenges and detoxifies free radicals and oxidants, increases intracellular thiol levels, controls nuclear factor-κB activation, and inhibits inflammatory gene expression.In addition, it inhibits the peroxynitrite-dependent nitration of nitrotyrosine, blocks oxidative DNA damage and cell death, and prevents the formation of xanthine and hypoxanthine. Ergothioneine is transported by the organic cation/carnitine transporter, which has been linked with autoimmune diseases, including rheumatoid arthritis and Crohn’s disease.
