Product name: Forsythoside E
Synonym name:
Catalogue No.: BP1634
Cas No.: 93675-88-8
Formula: C₂₀H₃₀O₁₂
Mol Weight: 462.448
Botanical Source: Forsythia suspensa
Physical Description: Powder
Type of Compound: Phenylpropanoids

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.

References:

《Chinese Journal of Pharmaceutical Analysis》 2013-03    

Determination of forsythoside E in Tanreqing injection by LC-MS/MS    

To establish a liquid chromatography-tandem mass spectrometric method(LC-MS/MS)for the determination of Forsythoside E in Tanreqing injection.

METHODS AND RESULTS:

After being diluted,the sample was separated on an Agilent SB-C18 column(2.1 mm×15 mm,3.5 μm)for gradient elution with a mobile phase of acetonitrile-0.01% formic acid water-solution at a flow rate of 0.3 mL·min-1.Then the processed sample was analyzed by tandem mass spectrometer with negative-electrospray ionization(ESI)source,monitored under a multiple reaction monitoring(MRM)mode.The calibration curve showed a good linearity in the range of 47.5-950 ng·mL-1.The average recoveries(n=3)of low,middle and high concentrations were 99.0%,103.0%,95.2% with RSDs of 3.4%,1.5% and 1.0%,respectively.The content of Forsythoside E in 13 batches of Tanreqing injection samples was in the range of 0.077-0.145 mg·mL-1.

CONCLUSIONS:

The developed method can be used for the quantitative determination of Forsythoside E in Tanreqing injection.