Product name: Dendrobine
Synonym name:
Catalogue No.: BP0479
Cas No.: 2115-91-5
Formula: C16H25NO2
Mol Weight: 263.381
Botanical Source: Main alkaloid from Dendrobium spp., esp. Dendrobium nobile (Orchidaceae)
Physical Description: Cryst.
Type of Compound: Alkaloids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Dendrobine, isolated from Dendrobium nobile, an antagonist of β-alanine, taurine and of presynaptic inhibition in the frog spinal cord.[1]
Dendrobine has antitumor activity, it can inhibit the growth of A549 cells through inducing apoptosis, which was partially dependent on mitochondrial-mediated pathway; dendrobine treatment decreased mitochondrial membrane potential (MMP), improved the expression of Bax and inhibited the expression of Bcl-2, therefore it was supposed that dendrobine treatment decreased the MMP through regulating the expression of Bcl-2 and Bax; dendrobine releases cytochrome c and promotes caspase 9 activation indicating that dendrobine induces apoptosis is partially caspase-dependent.[2]
References:
[1] Yannakopoulou K. Brit J Pharmacol, 1983, 78(4):709–15.
[2] Song T . The HKU Scholars Hub, 2016.
[3] Shen G. Journal of Anhui Agricultural Sciences, 2009, 37(31):15248-9.
