Product name: Cratoxylone
Synonym name:
Catalogue No.: BP1730
Cas No.: 149155-01-1
Formula: C₂₄H₂₈O₇
Mol Weight: 428.481
Botanical Source: Garcinia mangostana; Cratoxylum cochinchinense; Garcinia dulcis
Physical Description:
Type of Compound: Xanthones

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
The product could be supplied from milligrams to grams. Inquire for bulk scale.
We provide solution to improve the water-solubility of compounds, thereby facilitating the variety of activity tests and clinic uses.

For Reference Standard and R&D, Not for Human Use Directly.

Description:

Cratoxylone exhibits potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with the IC₅₀ value belows 3 uM. 

References:

Antiplasmodial constituents from the fruit pericarp of Pentadesma butyracea.    

Bioassay-guided fractionation of the fruit pericarp of Pentadesma butyracea, using the antiplasmodial test, led to the isolation of a new xanthone, named pentadexanthone (1), together with six known compounds: Cratoxylone (2), α-mangostin (3), 1,3,5-trihydroxy-2-methoxyxanthone (4), garcinone E (5), (-)-epicathechin (6), and lupeol (7). The structure of 1 was elucidated by spectroscopic data analysis. An antiplasmodial assay was performed with the isolates, in which compounds 1- 3 and 5 exhibited potent activity in vitro against Plasmodium falciparum chloroquine-resistant strain W2, with IC₅₀ values below 3 μM.