Product name: Beta-Ecdysterone
Synonym name: Ecdysterone; crustecdysone
Catalogue No.: BP0262
Cas No.: 5289-74-7
Formula: C27H44O7
Mol Weight: 480.642
Botanical Source: Cyanotis arachnoides C.B.Clarke
Physical Description: Powder
Type of Compound: Steroids
Purity: 95%~99%
Analysis Method: HPLC-DAD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Beta-Ecdysterone slowly reduces food consumption and then indirectly induces a state of starvation resulting in the elevation of the mRNA levels of InR , IRS , PI3K110 , and PDK in the Bombyx fat body during molting and pupation, and Beta-Ecdysterone inhibits innate immunity in the fat body during Bombyx postembryonic development.[1,2]
Beta-Ecdysterone acts as both a positive and a negative regulator of EDG transcription, sequences in the promoter regions of two of the EDGs are similar to an ecdysone response element and may play a role in negative regulation.[3]
Beta-Ecdysterone can block TORC1 activity for autophagosome initiation, and upregulates Atg genes to induce autophagy in the Bombyx fat body.[4]
References:
[1] Ling T, Guo E, Diao Y, et al. Bmc Genomics, 2010, 11(1):1-12.
[2] Yan L, Zhou S, Li M, et al. J Insect Physiol, 2010, 56(10):1436-44.
[3] Apple R T, Fristrom J W. Dev Biol, 1991, 146(2):569-82.
[4] Tian L, Ma L, Guo E, et al. Autophagy, 2013, 9(8):1172-87.
[5] Kim J H, Kim J M, Kang D H. ResearchGate, 2008, 23(1).
