Product name: Artemitin
Synonym name: Artemisetin; Erianthin; O-Pentamethylquercetagetin
Catalogue No.: BP1774
Cas No.: 479-90-3
Formula: C20H20O8
Mol Weight: 388.372
Botanical Source: Artemisia spp., Kuhnia eupatorioides
Physical Description: Yellow powder
Type of Compound: Flavonoids
Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Storage: Store in a well closed container, protected from air and light. Put into refrigerate or freeze for long term storage.
Whenever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20℃. Generally, these will be useable for up to two weeks.
The product could be supplied from milligrams to grams, up to kilograms
Inquire for bulk scale.
Descriptions:
Artemetin is one of the main components of Achillea millefolium L. and Artemisia absinthium , it improves cell viability in PAE that were subjected to peroxidation by counteracting GSH depletion and apoptosis and through the modulation of mitochondrial function, it protects endothelial function by acting as antioxidant and antiapoptotic agent and through the activation of ERK1/2 and Akt. [1]
Artemetin inhibits the viability of HeLa cells in a dose dependent manner,with IC50 of 79.9 μmol·L-1, it also induces the apoptosis of HeLa cells in a dose dependent manner. [2]
Artemetin has anti-inflammatory activity and sub-acute toxicity. [3]
Artemetin, isolated from Cordia curassavica DC, has antiedematogenic activity. [4]
References:
[1] Grossini E, Marotta P, Farruggio S, et al. Phytotherapy Research Ptr, 2015, 29(9).
[2] Yang X H, Tian L, Cao J G, et al. Central South Pharmacy, 2010, 08(8):568-71.
[3] Sertié, J. A. A, Basile, A. C, Panizza, S, et al.Planta Med, 1990, 56(1):36-40.
[4] Bayeux M C, Fernandes A T, Foglio M A, et al. Braz J Med Biol Res, 2002, 35(10):1229-32.
[5] Shi S, Zhou H, Zhang Y, et al. J Chromatogr Sci, 2009, 47(5):349-53.
