Synonym name: Techtochrysin; Techtochrysine; Tectochrysin
Catalogue No.: BP0103
Cas No.: 520-28-5
Formula: C₁₆H₁₂O₄
Mol Weight: 268.268
Botanical Source: Alpinia oxyphylla Miq.

Purity: 95%~99%
Analysis Method: HPLC-DAD or/and HPLC-ELSD
Identification Method: Mass, NMR
Packing: Brown vial or HDPE plastic bottle
Can be supplied from milligrams to grams.

For Reference Standard and R&D, Not for Human Use Directly.
Inquire for bulk scale.

Description:

Tectochrysin is a promising inhibitor for the reversal of ABCG2-mediated drug transport, it leads to apoptotic cell death in NSCLC cells through activation of DR3 and Fas expression via inhibition of STAT3 phosphorylation.Tectochrysin has antioxidant effect, it also exhibits a significant hepatoprotective activity in hepatic damage induced by CCl4-intoxication in rats.

References:

Arch Pharm Res. 2003 Jan;26(1):43-6.    

In vivo anti-oxidant activities of tectochrysin.   

The anti-oxidant activities of Tectochrysin, a major compound of propolis, were investigated. 

METHODS AND RESULTS:

Tectochrysin exhibited a significant decrease in serum transaminase activities elevated by hepatic damage induced by CCl4-intoxication in rats. Tectochrysin tested exhibited a lipid peroxidation causing a significant decrease in MDA production in TBA-reactant assay. Tectochrysin was strong in the increase in the anti-oxidant enzymes such as hepatic cytosolic superoxide dismutase, catalase and glutathione peroxidase activities in CCl4-intoxicated rats. 

CONCLUSIONS:

These results suggest that Tectochrysin possess not only the anti-oxidant, but also the activities in CCl4-intoxicated rats. Especially, Tectochrysin was found to cause significant increases in the rat liver cytosolic SOD, catalase, GSH-px activities as well as a significant decrease in the MDA production. 

HPLC of Techtochrysin